Your comprehensive guide to Semaglutide, Tirzepatide, and Retatrutide. Compare medications, understand the science, and find your ideal weight loss solution with expert guidance.
GLP-1 receptor agonists are a revolutionary class of medications that mimic natural hormones to help you lose weight effectively and safely.
GLP-1 medications work by mimicking the hormone glucagon-like peptide-1, which signals your brain when you're full. This naturally reduces hunger and cravings without the constant battle of willpower.
These medications slow down how quickly food leaves your stomach, keeping you satisfied longer after meals. This means smaller portions feel more satisfying and you naturally eat less.
Originally developed for diabetes, GLP-1s help regulate blood sugar by increasing insulin production when needed. This dual benefit makes them especially effective for those with metabolic concerns.
Across multiple clinical trials, GLP-1 medications have consistently demonstrated significant weight loss results when combined with lifestyle modifications. The newest generation shows even greater efficacy.
Understand the differences between each medication to make an informed decision with your healthcare provider.
| Feature | Semaglutide | Tirzepatide | Retatrutide |
|---|---|---|---|
| Brand Names | Ozempic, Wegovy | Mounjaro, Zepbound | Investigational (LY3437943) |
| Mechanism | GLP-1 agonist | GIP + GLP-1 dual agonist | GIP + GLP-1 + Glucagon triple agonist |
| Average Weight Loss | 15-17% | 20-22% | 24%+ (Phase 2 trials) |
| Administration | Weekly injection | Weekly injection | Weekly injection |
| Dosing Strengths | 0.25mg to 2.4mg | 2.5mg to 15mg | 1mg to 12mg |
| Time to Results | 4-8 weeks | 4-8 weeks | 4-6 weeks |
| Clinical Evidence | Extensive (STEP trials) | Strong (SURMOUNT trials) | Emerging (Phase 2 complete) |
| FDA Approval | Yes (2021) | Yes (2023) | Pending (expected 2025-26) |
| Best For | First-time users, proven track record | Maximum efficacy seekers | Cutting-edge, early adopters |
| Price (Monthly) | Contact for pricing | Contact for pricing | Contact for pricing |
Note: All medications are compounded versions with the same active ingredients as brand-name products. Your consultation will help determine which option is best suited for your health profile and goals.
Answer 3 quick questions to get a personalized recommendation.
What is your primary weight loss goal?
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What is your budget preference?
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What is your experience with weight loss medications?
Based on your answers, Semaglutide is your ideal starting point. It's the most proven GLP-1 with extensive clinical data, making it perfect for first-time users who want reliable, well-documented results.
Based on your answers, Tirzepatide is your ideal choice. Its dual-action mechanism offers superior weight loss results compared to single-agonist options, perfect for those seeking significant transformation with proven clinical backing.
Based on your answers, Retatrutide is your ideal choice. As the most advanced triple-agonist available, it offers the highest potential for weight loss. Perfect for early adopters who want cutting-edge treatment and maximum results.
All three generations of GLP-1 medications, sourced from verified compounding partners with guaranteed authenticity.
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Understanding the biological mechanisms behind these revolutionary weight loss treatments.
GLP-1 receptors in the hypothalamus receive signals that reduce appetite and increase satiety, making you feel satisfied with less food.
The medications slow gastric emptying, keeping food in your stomach longer. This extends the feeling of fullness after meals.
GLP-1s stimulate glucose-dependent insulin secretion from the pancreas, helping regulate blood sugar levels naturally.
By reducing glucagon secretion, these medications help prevent excess glucose production by the liver.
The evolution of GLP-1 medications has moved from targeting a single receptor to multiple receptors simultaneously, each adding new mechanisms for weight loss.
We've simplified the process to get you started safely and quickly. Every step is designed with your health and convenience in mind.
Chat with our medical team about your goals, health history, and which medication might be right for you. No pressure, no commitment.
15-20 minutesComplete a brief health questionnaire reviewed by our licensed physicians. We'll ensure GLP-1 therapy is safe and appropriate for you.
24-48 hoursOnce approved, receive your prescription and complete payment via bank transfer or card. Secure and confidential.
Same dayYour medication is shipped in temperature-controlled packaging to maintain integrity. Delivered discreetly to your home or office.
Lagos: 24hrs | Nationwide: 48-72hrsOur team is available via WhatsApp for injection guidance, side effect management, and progress check-ins throughout your journey.
Unlimited supportAll medications sourced from licensed compounding pharmacies with full chain of custody documentation.
Licensed Nigerian physicians review every case and provide ongoing medical oversight.
Temperature-controlled storage and delivery ensures medication potency from warehouse to your door.
Reach our team anytime via WhatsApp for questions, guidance, or concerns. Real people, real answers.
Get answers to the most common questions about GLP-1 medications in Nigeria.
Semaglutide is a GLP-1 receptor agonist - the original weight loss medication in this class. It's well-studied with extensive clinical data showing 15-17% average weight loss.
Tirzepatide is a dual GIP/GLP-1 agonist, targeting two receptors instead of one. This dual mechanism leads to greater weight loss (20-22% average) and improved metabolic effects.
Retatrutide is the newest triple agonist, targeting GLP-1, GIP, and glucagon receptors. Phase 2 trials showed up to 24% weight loss, making it the most potent option available.
The best medication depends on several factors: your weight loss goals, medical history, budget, and tolerance for newer treatments. Generally:
Our free consultation will help determine the best fit based on your specific situation.
We provide compounded versions that contain the same active ingredients as the brand-name medications. Ozempic and Wegovy are brand names for semaglutide, while Mounjaro and Zepbound are brand names for tirzepatide.
Compounded medications are prepared by licensed compounding pharmacies and offer the same therapeutic benefits at a more accessible price point. All our products are sourced from verified, licensed facilities.
The most common side effects across all GLP-1 medications are gastrointestinal and typically decrease over time:
Most side effects are mild and temporary. Our gradual dose titration protocol helps minimize these effects, and our medical team provides guidance for managing any discomfort.
Most patients notice reduced appetite and some weight loss within the first 2-4 weeks. Significant weight loss typically becomes visible after 8-12 weeks as you progress through dose titration.
Clinical trials show the following timelines for maximum effect:
Results vary based on starting weight, diet, exercise, and individual metabolism.
All GLP-1 medications require refrigeration (2-8C). We ship in insulated, temperature-controlled packaging with ice packs to maintain the cold chain.
Delivery times:
Once received, store in your refrigerator (not freezer). Opened vials remain effective for 28-30 days when refrigerated.
Yes. GLP-1 medications require a prescription from a licensed physician. Our service includes a medical consultation where a Nigerian-licensed doctor reviews your health information and, if appropriate, provides a prescription.
The consultation is free with no obligation. If our doctors determine GLP-1 therapy isn't suitable for you, we'll explain why and suggest alternatives.
Yes, you can switch between GLP-1 medications under medical supervision. Common reasons to switch include:
Our medical team will guide you through any transition, adjusting dosages appropriately to ensure safety and effectiveness.
Get a free consultation with our medical team to discuss which medication is right for you. No pressure, no commitment - just expert guidance.